D This HRA Call for Comments closed on 30 September 2016. If you have any comments or questions, please contact Jennifer de Beyer on jennifer.de-beyer@csm.ox.ac.uk. Kind regards, Prof Doug Altman, Dr Iveta Simera, and Dr Jennifer de Beyer EQUATOR Network Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford www.csm.ox.ac.uk

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