Steatosis in frozen sections from potential liver donors |
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In preparation for the British Liver Transplant Group meeting in York in September, this is a small study of inter-observer variation in the reporting of donor liver biopsies sent for assessment of steatosis. It will probably take you 20-30 minutes to do.
The study will be in two parts - at this first stage, please will you report the cases with an estimate of the % hepatocytes showing macrovesicular steatosis, and a comment if required. Please also indicate in the question at the beginning if you normally estimate a % of steatosis or report on a scale of none/mild/moderate/severe, and whether you separately assess macro and microvesicular steatosis. You may report other abnormalities in the biopsy.
We plan to follow this initial phase with a re-labelling of the slides, and then a second round with guidance on reporting and a repeat assessment of inter-observer variation.
Please will you encourage all the pathologists who provide this out of hours service to take part in the study. Please include your name and transplant centre - if you feel uncomfortable about doing this please make up a nickname for yourself which you will use again in the second part of the study - (but you will not be able to claim a CPD point if you do this).
many thanks for your help,
Judy and Desley.
The study will be in two parts - at this first stage, please will you report the cases with an estimate of the % hepatocytes showing macrovesicular steatosis, and a comment if required. Please also indicate in the question at the beginning if you normally estimate a % of steatosis or report on a scale of none/mild/moderate/severe, and whether you separately assess macro and microvesicular steatosis. You may report other abnormalities in the biopsy.
We plan to follow this initial phase with a re-labelling of the slides, and then a second round with guidance on reporting and a repeat assessment of inter-observer variation.
Please will you encourage all the pathologists who provide this out of hours service to take part in the study. Please include your name and transplant centre - if you feel uncomfortable about doing this please make up a nickname for yourself which you will use again in the second part of the study - (but you will not be able to claim a CPD point if you do this).
many thanks for your help,
Judy and Desley.