Journal club MCQ July 2019

Diagnostic accuracy of saline contrast sonohysterography in detecting endometrial polyps in women...

Objective of article

In women with postmenopausal bleeding, endometrial polyps are a frequent finding and the risk of a focal (pre)malignancy in a polyp is up to 6%. Because of this reported risk, the detection of polyps in these women, preferably by a minimally invasive method, is important. The aim of this systematic review was to assess the accuracy of saline contrast sonohysterography (SCSH) for diagnosis of endometrial polyps in women with postmenopausal bleeding

Question Title

* 1. According to this manuscript, what is the suggested cut-off for endometrial thickness that warrants further diagnostic testing in women with postmenopausal bleeding?

a. 1 mm

b. 2 mm

c. 4 mm

d. 6 mm

e. 8 mm

Question Title

* 2. What is the reported risk for a focal (pre)malignancy in an endometrial polyp in women with postmenopausal bleeding?

a. Less than 1%

b. 4-6%

c. 10-15%

d. 15-20%

e. More than 20%

Question Title

* 3. What is the reported prevalence of endometrial polyps in women with postmeopausal bleeding and a thickened endometrium?

a. 15%

b. 20%

c. 40%

d. 50%

e. 80%

Question Title

* 4. Which of the following statements is true regarding saline contrast sonohysterography according to the results of this systematic review and meta-analysis

a. The overall between study heterogeneity was high, limiting the comparability of the included studies.

b. The sensitivity and specificty of sonohysterography was low (less than 60%).

c. The results obtained in this systematic review are also appilcable to women with PMB using tamoxifen.

d. The overall procedure failure rate was low (less than 2 cases per 10 attempts) for SCSH and was mainly due to cervical stenosis.

Question Title

* 5. Which of the following is true regarding strengths and limitations of this systematic review?

a. An important limitation is the low number of included patients in each study.

b. A notable strength is the high number of eligible studies for a meta-analysis.

c. Publication bias does not apply to this study.

d. A noteable strength is the high number of included patients in each study.