PIVOTAL Implementation in the UK |
PIVOTAL
Dear all
I would be grateful if you could spend a few minutes completing this brief survey to understand whether your unit has implemented the results of the PIVOTAL study which you may have participated in and what percentage of all hemodialysis patients (both prevalent and incident) would be eligible based on the criteria I have highlighted.
I would be grateful if you could spend a few minutes completing this brief survey to understand whether your unit has implemented the results of the PIVOTAL study which you may have participated in and what percentage of all hemodialysis patients (both prevalent and incident) would be eligible based on the criteria I have highlighted.
As reminder the inclusion exclusion criteria were
INCLUSION CRITERIA
>18 years
CRP <50
On HD for <1 year (incident)
INCLUSION CRITERIA
>18 years
CRP <50
On HD for <1 year (incident)
SF <400
TS <30%
TS <30%
On ESA therapy
EXCLUSION CRITERIA
ALT >x3 normal
Advanced NYHA IV heart failure
Planned Tx in next 12 months
Life expectancy <12 months
Active malignancy
ACTIVE infection
Planned Tx in next 12 months
Life expectancy <12 months
Active malignancy
ACTIVE infection
And the Proactive regime was
IV iron 600mg in the first month and then 400mg per month – withhold if SF >700 or TS%> 40
Given as 200mg for first 3 sessions on randomization then 200mg on 2 occasions in the next month and then monthly